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| Rank | Company Name | Market Capital | Headquarters Country |
| 1 | Eli Lilly | $796.40 B | United States |
| 2 | Novo Nordisk | $530.70 B | Denmark |
| 3 | Johnson & Johnson | $389.94 B | United States |
| 4 | AbbVie | $196.96 B | United States |
| 5 | Merck | $290.84 B | United States |
| 6 | Roche | $243.92 B | Switzerland |
| 7 | Astrazeneca | $215.41 B | United Kingdom |
| 8 | Novartis | $231.91 B | Switzerland |
| 9 | Amgen | $172.11 B | United States |
| 10 | Pfizer | $162.46 B | United States |
| 11 | Sanofi | $144.05 B | France |
| 12 | Vertex Pharmaceuticals | $121.24 B | United States |
| 13 | Regeneron Pharmaceuticals | $115.40 B | United States |
| 14 | Bristol-Myers Squibb | $107.24 B | United States |
| 15 | Gilead Sciences | $104.50 B | United States |
| 16 | CSL | $92.62 B | Australia |
| 17 | Zoetis | $88.08 B | United States |
| 18 | GlaxoSmithKline | $82.77 B | United Kingdom |
| 19 | Chugai Pharmaceutical | $79.36 B | Japan |
| 20 | CVS Health | $77.41 B | United States |
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(updated on 2-Oct-2024)